Publications

------ Mravic Lab @ Scripps ------

Ab initio prediction of specific phospholipid complexes and membrane association of HIV-1 MPER antibodies by multi-scale simulations. CA Maillie, J Golden, IA Wilson, AB Ward, M Mravic. bioRxiv, 2023.05. 04.539433. 2023


------ from Marco @ UCSF ------

Mravic M*, He L*, Kratochvil H, Hu H, Nick SE, Bai W, Edwards A, Jo H, Wu Y, DiMaio D, DeGrado WF. "Designed Transmembrane Proteins Inhibit the Erythropoietin Receptor in a Custom Binding Topology," (2023) bioRxiv 2023.02.13.526773. DOI: https://doi.org/10.1101/2023.02.13.526773

Kratochvil HT, Watkins LC, Mravic M, Thomaston JL, Nicoludis JM, Somberg NH, Liu L, Hong M, Voth GA, DeGrado WF. "Transient water wires mediate selective proton transport in designed channel proteins," Nat Chem (2023) Epub. PMID: 37308712

Scott AJ, Niitsu A, Kratochvil HT, Lang EJM, Sengel JT, Dawson WM, Mahendran KR, Mravic M, Thomson AR, Brady RL, Liu L, Mulholland AJ, Bayley H, DeGrado WF, Wallace MI, Woolfson DN. "Constructing ion channels from water-soluble α-helical barrels," Nat Chem (2021) 13(7):643-650. PMID: 33972753

Clark IC, Mensa B, Ochs CJ, Schmidt NW, Mravic M, Quintana FJ, DeGrado WF, Abate AR. "Protein design-scapes generated by microfluidic DNA assembly elucidate domain coupling in the bacterial histidine kinase CpxA," PNAS (2021) 118(12). PMID: 33723045

Mravic M, Thomaston JL, Tucker M, Solomon P, Liu L, DeGrado WF. “Packing of Apolar Side Chains Enables Accurate Design of Highly Stable Membrane Proteins,” Science (2019) 363(6434), 1418-23

Litvinov RI*, Mravic M*, Zhu H, Weisel JW, DeGrado WF, Bennett JS. “Unique Transmembrane Domain Interactions Differentially Modulate Integrin αvβ3 and αIIbβ3 Function,” PNAS (2019) 116(25):12295-12300

Dang B, Mravic M, Hu H, Schmidt N, Mensa B, DeGrado WF. “SNAC-Tag for Sequence-specific Chemical Protein Cleavage,” Nature Methods (2019) 16, 319-22

*Mravic M, *Hu H, Lu Z, Bennett JS, Sanders CS, Orr AW, DeGrado WF. “De Novo Designed Transmembrane Peptides Activating the α5β1 Integrin,” Protein Engineering, Design, and Selection (2018) 31(5),181-190

Pahuja KB, Nguyen TT, Jaiswal BS, Prabhash K, Thaker TM, Senger K, Chaudhuri S, Kljavin NM, Antony A, Phalke S, Kumar P, Mravic M, Stawiski EW, Vargas D, Durinck S, Gupta R, Gupta AK, Trabucco SE, Sokol ES, Hartmaier RJ, Singh A, Chougule A, Trivedi V, Dutt A, Patil V, Joshi A, Noronha V, Ziai J, Banavali SD, DeGrado WF, Bueno R, Jura N, Seshagir S. “Actionable activating oncogenic ERRB2/HER2 Transmembrane and Juxtamembrane domain mutations,” Cancer Cell (2018) 34(5), 792-806

*Dang B, *Wu H, *Mulligan V, Mravic M, Wu Y, Lemmin T, Ford A, Silva DA, Baker D, DeGrado WF. “De Novo Design of Covalently Constrained Meso-size Protein Scaffolds with Unique Tertiary Structures,” PNAS (2017) 114(41), 10852-10857.

Mavor D, Barlow K, Thompson S, Barad BA, Bonny AR, Cario CL, Gaskins G, Liu Z, Deming L, Axen SD, Caceres E, Chen W, Cuesta A, Gate RE, Green EM, Hulce KR, Ji W, Kenner LR, Mensa M, Morinishi LS, Moss SM, Mravic M, Muir RK, Niekamp S, Nnadi CI, Palovcak E, Poss EM, Ross TD, Salcedo EC, See SK, Subramaniam M, Wong AW, Thorn KS, Conchúir SÓ, Roscoe BP, Chow ED, DeRisi JL, Kortemme T, Bolon DN, Fraser JS. “Determination of Ubiquitin Fitness Landscapes Under Different Chemical Stresses in a Classroom setting,” eLife (2016) 5, e15802.

*Zhang SQ, *Kulp DW, *Schramm CA, Mravic M, Samish I, DeGrado WF. “The Membrane-and Soluble-Protein Helix-Helix Interactome: Similar Geometry via Different Interactions,” Structure (2015) 23(3), 527-41.

------ @ UCLA ------

Shen J, Shrestha S, Yen YH, Asatrian G, Mravic M, Soo C, Ting K, Dry SM, Peault B, James AW. “Pericyte Antigens in Perivascular Soft Tissue Tumors,” International Journal of Surgical Pathology (2015). 23(8), 638-48.

Mravic M, LaChaud G, Nguyen A, Scott MA, Dry SM, James AW. “Clinical and Histopathological Diagnosis of Glomus Tumor: An Institutional Experience of 138 Cases,” International Journal of Surgical Pathology. (2015) 23(3), 181-8.

Mravic M, Nguyen A, Scott MA, James AW. “Emerging signaling pathways for future therapies in Osteosarcoma: Wnt, Notch and Hedgehog signaling,” In: Choy E, Osteosarcoma: Symptoms, Diagnosis and Treatment Options (2014) 201-226. NY: Nova Pub.

Mravic M, Péault B, James AW. “Current Trends in Bone Tissue Engineering,” BioMed Res. Int. (2014) 1-5.

Mravic M, Asatrian G, Soo C, Lugassy C, Barnhill RL, Dry SM, Peault B, James AW. “From pericytes to perivascular tumors: correlates between pathology, stem cell biology, and tissue engineering,” Int. Orthop. (2014) 38(9), 1819-24.